Lab sample filter membrane syringe filter for HPLC sample preparation

The sterile syringe filter provided by Aijiren has a cellulose acetate or PES filter membrane. A sterile membrane with a pore size of 0.2um is an ideal material for sterilization and filtration, while a pore size of 0.45¦Ìm can be used for clarification. The sterile needle filter is sterilized by gamma radiation, which avoids the toxic residue caused by other sterilization methods

Polypropylene is compatible with acetone, ethyl acetate, methanol, isobutanol, methanol and methyl ethyl ketone. Polypropylene is incompatible with cyclohexane, ether, dichlorobenzene, pentane, methylene chloride and trichlorobenzene. It is recommended to use gas, disinfectant or autoclave to sterilize products made of polypropylene. The maximum operating temperature is 135¡ãC.

Syringe filter is a small, disposable device used for filtration purposes in laboratories and other scientific settings. It consists of a plastic housing with a membrane filter at one end and a female luer lock or male luer slip connection at the other end, allowing it to be attached to a syringe.
The purpose of a syringe filter is to remove impurities, particulates, or unwanted substances from a liquid sample before it is injected or analyzed. The membrane filter within the syringe filter acts as a barrier, selectively allowing only certain particles or molecules to pass through while retaining larger particles.

Aijiren disposable syringe filter devices are designed to provide fast and efficient filtration of aqueous and organic solutionsfrom small volumes up to 100 mL.

The PES film is sealed in the polymer shell without the use of any adhesive. Each unit can provide ETO or Gamma radiation disinfection, and ensure that there is no pyrogen.

Another way to determine the micron size of columns, 0.45 um for >3 um, and 0.22 um for <3um. 0.45 um membranes are typically used for general filtration and particle removal while 0.2/0.22um membranes, or sterilizing-grade membranes, are most commonly used for solution sterilization (bacteria removal).

In HPLC analysis, the particle size of the chromatographic column packing is small and easily blocked by contaminant particles. Therefore, samples and solvents must be pre-filtered to remove particulate contaminants and protect the instrument.

PES syringe filter is hydrophilic in nature, and has low protein binding, high flow rate and excellent chemical stability. In addition, it also contributes to oxidation stability, high heat and low concentration of extractable elements.

The Sterile syringe filter produced by Aijiren is a single-use membrane-based filtration facility that is mostly used to remove particulate impurities from liquid and gas samples before analysis by HPLC, ion chromatography, gas chromatography, ICP, and dissolution testing methods. . Correctly filtering samples in chromatographic experiments can improve the quality and consistency of analysis results and reduce instrument downtime. The sterile syringe filter adopts high-temperature aseptic processing and vacuum packaging of liquid to ensure the cleanliness of the syringe filter. It is recommended to be used once.

Sample preparation for high-throughput Ultra High Performance Liquid Chromatography (UHPLC)/High Performance Liquid Chromatography (HPLC) analysis can be time consuming when using multiple consumables such as a syringe, syringe filter, sample vial, cap, and septum. Aijiren HPLC filters result in faster sample preparation than the normal syringe filter method.

Syringe filter is a disposable filter unit designed to remove impurities from liquids or gases using a syringe as the fluid delivery system.
It consists of a plastic housing with an inlet and an outlet, and a filter membrane positioned between them.
The filter membrane is often made of materials such as polypropylene, polytetrafluoroethylene (PTFE), or nylon.
To use a syringe filter, the liquid or gas to be filtered is drawn into a syringe, and then the syringe is attached to the inlet of the syringe filter.

The Nylon Syringe Filter produced by Aijiren is mostly used for reagent filtration or sample preparation. Nylon Syringe Filter has different specifications. The filter membrane diameter is 13mm, 25mm and 33mm, which can be selected according to the capacity of the sample. Aijiren provides 0.22μm and 0.45. Two μm specifications are convenient for customers to choose. The Nylon Syringe Filter produced by Aijiren meets customers’ requirements and needs for product preparation.

Syringe Filters with hydrophobic PTFE membranes can be used for filtration of strong solvents, acids and alkalis. Not suitable for filtration of aqueous liquids. Filters with hydrophilic PTFE can be used for filtration of strong solvents, acids and alkalis. However, these syringe filters can also be used for the filtration of aqueous liquids, which makes this type very versatile.

MCE features: relatively uniform pore size, high porosity, no media shedding, thin texture, low resistance, fast filtration rate, and minimal adsorption.
The main purpose of MCE: to filter out the particles and bacteria of liquid medicine, gas, oil, beverages, sprinkles, electronic instruments, etc., and can also be used for the detection of particles and bacteria.

With PES syringe filter membrane mechanically strong character, it can handle high-temperature liquids, with great flow rate (better than PTFE), and low protein binding. With these features, PES syringe filters offer superior performance for use with biological samples and media culture. Workable pH range ~3-14.
Nylon: Nylon membrane filters are hydrophilic, flexible, tear-resistant, and autoclavable. They are resistant to a range of organic solvents and suitable for use with high pH samples. Nylon binds proteins. Unsuitable for acidic solutions. pH range ~3-14.
MCE (Mixed Cellulose Ester) syringe filters are an ideal choice when biological samples are involved. Mixed Cellulose is a hydrophilic membrane offering both low protein binding coefficients and exceptional flow rates.

The PVDF Syringe Filter produced by Aijiren is made of high-quality raw materials. The filter membrane is very suitable for sample preparation and reagent filtration. Aijiren believes that the PVDF Syringe Filter can be integrated with water-based reagents, and the hydrophilicity ensures that the PVDF Syringe Filter can filter water-based reagents. success.

Our syringe filters are high quality, packaged and sold at fair competitive prices. They are available in most of the major membrane materials including nylon, PTFE, PES, MCE, PVDF, CA, PP, and GF, and are available in 13mm, 17mm, 25mm and 30mm formats for virgin polypropylene housings.

Nylon has excellent flow characteristics, extremely low extractable level and mechanical stability, and can provide the best combination of physical parameters to meet the most stringent analysis requirements of 13mm, 25mm and 33mm diameters. Nylon’s natural hydrophilicity, high protein binding capacity and high dirt adsorption capacity are natural advantages.

Cellulose acetate is a very low protein binding membrane that is ideal for aqueous based samples and biological samples. It is a lower protein binder than either polyethersulphone or PVDF membranes, but has a lower chemical resistance than regenerated cellulose (RC). CA is a strong membrane mechanically and hydrophilic.

Choice PES Syringe Filters Specifications
Membrane: HPLC certified
Maximum operating temperature: 100 ¡ãC
Housing: Medical grade, virgin polypropylene
Autoclave: Sterilize by dry heat at 121 ¡ãC for 15 minutes

The syringe filter has the following characteristics:
1. Convenient, readily available, easy to operate, economical and practical.
2. Reliable bacteria retention efficiency ensures the filtering and sterilization effect.
3. Larger effective membrane filtration area: 1.09cm2.
4. High flow rate, high throughput, dead volume no more than 10¦Ìl.
5. Very low protein adsorption.
6. Pass HPLC dissolution test.

The syringe filters are available in various pore sizes and membrane materials to accommodate different filtration requirements. They are suitable for a wide range of laboratory applications, including sample preparation, clarification, and sterilization. The filters provide reliable performance and consistent filtration results, contributing to accurate and reproducible data in analytical chemistry, microbiology, and other fields.

1. The pore size of the needle-punched membrane is accurate, providing comprehensive protection for your instrument and chromatographic column
2. There is a clear label on the Nylon syringe filter to avoid confusion
3. The luer interface of the needle filter with lock can prevent the filter from flying out due to excessive pressure

Chromatography commonly used in environmental analysis requires that no inorganic contaminants be introduced during sample pretreatment. In HPLC analysis and IC analysis, syringe filters can be used to filter sample solutions, which is an important step in sample pretreatment.

Features of the syringe filter: Luer lock inlet provides a sealed syringe connection, with various filter types, porosities and diameters. Color coding is easy to identify. Rugged polypropylene shell. Can be autoclaved to 121℃ for 15 minutes. The quantity exceeds the minimum order quantity to save more.